Ohio State owns three straight victories over rival Penn State, seven wins in the last nine meetings between the teams and a 6-3 record against the spread over that same span. The unbeaten Buckeyes shoot for a fourth straight win over the Nittany Lions Saturday night at the Horseshoe in Columbus.
Point spread: The Buckeyes opened as 17.5-point favorites, according to sportsbooks monitored by Odds Shark. (Line updates and matchup report)
College football pick, via Odds Shark computer: 40.9-18.4 Buckeyes
Why the Penn State Nittany Lions can cover the spread
The Lions are off to a 5-1 start to this season after beating Indiana last week 29-7 and easily covering as four-point home favorites.