The Penn State Nittany Lions are 3-0 both outright and against the spread in their last three meetings with the Iowa Hawkeyes, including a dominating victory/cover last season. The Nittany Lions look to keep their train rolling when they meet the Hawkeyes in the Big Ten opener for both teams Saturday night in Iowa City.
College football point spread: The Nittany Lions opened as 13.5-point favorites, according to sportsbooks monitored by OddsShark. (Line updates and matchup report)
College football betting pick, via OddsShark computer: 43.2-20.4 Nittany Lions (College football picks on every game)
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