It's a rivalry that's spanned 123 years and 96 meetings, 21 U.S. presidents and 46 College Football Hall of Famers.
But one Pitt-Penn State game stands above all the rest.
Thirty-five years ago -- on Nov. 28, 1981 -- the Penn State Nittany Lions completed one of the biggest upsets in school history, not necessarily by whom they beat but by how they won. They entered a hostile environment to take on the No. 1 Pittsburgh Panthers, a touchdown favorite, and found themselves trailing 14-0 after the first quarter.
They ended up winning 48-14.
Some fans might have turned off the national ABC broadcast 15 minutes into the game.