Oklahoma State is 3-1 both straight up and against the spread in four meetings with TCU since the latter joined the Big 12 four years ago. The Cowboys shoot to stay alive in this season's Big 12 race when they battle the Frogs on Saturday afternoon down in Fort Worth.
Point spread: The Horned Frogs opened as 4.5-point favorites, according to sportsbooks monitored by Odds Shark (line updates and matchup report).
College football pick, via Odds Shark computer: 38.4-38.2 Cowboys (College football picks on every game)
Why the Oklahoma State Cowboys can cover the spread
Since starting 2-2 start this season OSU is 6-0 SU and 4-2 ATS after outlasting Texas Tech last week 45-44.