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Oklahoma State Cowboys vs. Oklahoma Sooners Odds, College Football Betting Pick

Oklahoma owns the upper hand in the recent Bedlam rivalry with Oklahoma State, winning 13 of the last 15 meetings straight up, including the last three, going 7-3 against the spread over the last 10. The Sooners are favored to extend their dominance over the Cowboys when the teams meet for the 113th time on Saturday afternoon in Norman.

College football point spread: The Sooners opened as 18-point favorites, according to sportsbooks monitored by OddsShark. (Line updates and matchup report)

College football betting pick, via OddsShark computer: 48.4-32.0 Sooners (College football picks on every game)

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