go head-to-head with the Arizona Cardinals (+9.5) in Mexico City.
This has been quickly judged as a one-sided affair as the Cardinals will be without their franchise quarterback, Kyler Murray. However, wide receiver DeAndre Hopkins is active.
The odds from DraftKings Sportsbook for tonight are rather reflective of Murray’s absence and the 49ers’ recent improvements as they enter on a two-game winning streak.
Odds
Spread: 49ers -10
Over/Under: 43
Moneyline: 49ers -435/ Cardinals +350
Picks
It’s a consensus pick kind of night with the Beatdown staff taking the 49ers to win this matchup.