The Royals scored four quick runs in the first two innings against Orioles starter Yovani Gallardo, who left after two innings.
O's third baseman Manny Machado homered in the sixth inning and now has a career-high 15-game hitting streak.
MOMENTS THAT MATTERED
Moose on the loose: Moustakas has been a pain to the Orioles since the 2014 American League Championship Series, when he homered twice. Last season, he hit .429 against the O's with four homers. On Friday, Moustakas hit a two-run homer in his first at-bat, then doubled in each of his next two at-bats.