Aston Villa goalkeeper Emiliano Martinez is expected to start despite being substituted after a blow to the head against Newcastle United.
Bruno Fernandes is suspended for Manchester United as a result of accumulating five yellow cards.
Victor Lindelof returned from illness to face Real Sociedad on Thursday, when Aaron Wan-Bissaka was back in the squad following a lengthy injury.
Manager Erik ten Hag says he is unsure whether Antony, Jadon Sancho or Anthony Martial will be fit for Sunday.
CHRIS SUTTON'S PREDICTION
Manchester United continue to impress me under Erik ten Hag - I like what he is doing with them and they keep finding a way to win games, like they did against West Ham on Sunday.