Jorginho and Kieran Tierney will leave Arsenal upon expiry of their contracts on 30 June, the club have announced via their retained list.
Italy midfielder Jorginho, who is set to sign for Brazilian side Flamengo, joined the Gunners in a £12m deal from Chelsea in January 2023 and went on to make 79 appearances.
Scotland international Tierney signed for the north London club from Celtic six years ago for a reported fee of £25m.
The left-back made 170 appearances before signing for La Liga club Real Sociedad on loan during the 2023-24 season.