Theo Walcott scores.
And Alex McCarthy saves Dominic Iorfa's spot-kick.
It's all over. Premier League Southampton beat League One Sheffield Wednesday on penalties.
Andrew Priestley: Chelsea will rue the fact that their best two chances of the game fell to Lewis Hall. In saying that, Chelsea were miles off it tonight. The new manager bounce has certainly worn off quickly for Graham Potter, who all of a sudden looks a bit lost.
Chris Painter: Graham Potter can't be taking the blame for this. His game plan has worked. They've created chances that ANY player in the Premier League should be taking, but they've not taken them.