Armenian midfielder Henrikh Mkhitaryan faces a spell on the sidelines having limped out of Thursday's Europa League quarter-final win over CSKA Moscow with a knee problem.
With Arsenal chasing Europa League glory and a return to Champions League football, Danny Welbeck's role could now become greater over the remainder of the season.
'He's got knee ligament damage,' Wenger revealed after Arsenal's victory over Southampton in the Premier League on Sunday afternoon.
'He will not be available for Thursday (v CSKA) and not for Newcastle and certainly not for the week after, I think we play West Ham.