Arsenal forward Theo Walcott could make his first league appearance for six weeks after scoring a hat-trick on his comeback from a calf problem in the FA Cup win at Southampton.
Danny Welbeck is unlikely to be risked from the start, while Granit Xhaka is still suspended.
Watford could give debuts to Mauro Zarate and M'Baye Niang, while Valon Behrami may be fit after a back injury.
Costel Pantilimon has an ankle injury and Jose Holebas is serving a ban.
MOTD COMMENTATOR'S NOTES
Jonathan Pearce: "Going by FA Cup form, this should be a comfortable sixth successive home league win for Arsenal.