Arsenal midfielder Thomas Partey has been left out of Ghana's squad for the 2023 Africa Cup of Nations (Afcon) in Ivory Coast because of injury.
Partey, 30, has been out since October with a hamstring problem.
"This is the biggest injury that he has had," Black Stars head coach Chris Hughton said.
"The most important thing for me as head coach and our association is to give him the support that he needs through this period of time."
He added: "Withstanding his injury, he certainly would be in the squad."
Brighton right-back Tariq Lampey also misses out because of injury but West Ham midfielder Mohammed Kudus, Bournemouth forward Antoine Semenyo and Leicester City defender Daniel Amartey are all in the 27-man squad.