The Arizona run defense will face its biggest 2025 challenge at Iowa State on Saturday. Iowa State has a productive trio at running back and quarterback Anthony Becht is a threat as a runner. Arizona has allowed 288 yards rushing in three games, with one carry going 75 yards for a touchdown by Kansas State.
Arizona is 29th nationally, allowing 96.0 rushing yards per game and 50th with opponents averaging 3.43 yards per carry. Kansas State had a season high 24 carries for 105 yards and the only two TDs allowed by the Arizona defense.
Iowa State is 70th nationally, averaging 161.