Arizona dominated Colorado, winning nine out of 13 games since the Buffaloes entered the Pac-12 in 2011. Colorado won 34-7 at Arizona in their first game as Big XII opponents during the 2024 season. Colorado has won 17 and lost 10 in the overall series against Arizona.
The Buffaloes won the first 12 games against the Wildcats. Colorado won 27-7 at Arizona in the first meeting between the Buffaloes and Wildcats in 1931. Only three out of the first 12 games in the series between Arizona and Colorado were one possession.
Arizona won its first game against Colorado 24-21 in 1986.