The Arizona Wildcats are 19-61-1 all-time against Top 10 college football teams, including earlier this season when they lost 49-22 to then-No. 8 Oregon.
Enter USC, which is ranked No. 10 in the country. The only loss for the Trojans (6-1, 4-1 Pac-12) came two weeks ago in a 43-42 setback at Utah.
Arizona (3-4, 1-3) is a 15-point underdog, according to DraftKings Sportsbook.
Who will win this matchup? Here’s what our staff thinks:
Kim Doss — USC wins 52-35
It’s pretty simple. Arizona doesn’t have the defense to contain the USC offense.