Goldschmidt will leave D-backs camp March 6 to take part in Team USA's first workout on March 7.
"I was really excited when they asked me if I would participate," Goldschmidt said. "It was something I wanted to do, but didn't know if I'd have the opportunity. It's fun to get to go out there and represent your country and the Diamondbacks and go compete against the best players in the world. It will be a very competitive tournament."
The World Baseball Classic runs from March 6-22. In the U.S., games will air live exclusively in English on MLB Network and on an authenticated basis via MLBNetwork.