The first quarter of the 2020 season couldn’t have gotten off to a worse start. Isaiah Simmons was flagged for a horse-collar tackle and then gave up a long 76-yard touchdown (that would likely not have been nearly as long if starting Safety Jalen Thompson hadn’t hobbled off with an injury).
On the offensive side? It was just as brutal, with the Cardinals’ offense looking similar to their 2019 Week 1 counterparts, rushing only 3 times in the first quarter and running a lot of the 10 personnel (4 receivers, 1 RB) sets that didn’t give Kyler Murray a lot of time in the pocket and saw penalties trying to stop the Niners’ pass rush.