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Arizona Cardinals to host Kansas City Chiefs in their 2022 NFL opener

The Arizona Cardinals kick the 2022 NFL season off with a bang.

The Cardinals will host the Kansas City Chiefs at 1:25 p.m. local time on September 11, 2022 for the first game of the regular season.

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Notes on the game from the team:

Arizona will open the season at home for the 10th time since beginning play at State Farm Stadium in 2006. In 18 seasons at Sun Devil Stadium the Cardinals never played at home in Week 1.