They are winless through three games of a six-game road trip, only able to grab a point in a shootout loss to Tampa Bay.
John Gibson will be the man in net for Anaheim, while opposite of him will be Robin Lehner for Buffalo.
Lehner is coming off a 37-save performance versus the Devils three nights ago, in a losing effort.
The opening face-off at KeyBank Center is 4 P.M. Pacific on Prime Ticket and AM 830 KLAA.
Anaheim Ducks (28-17-10, 66 points)
Switching It Up:
Head Coach Randy Carlyle has not be happy with the results from his team, so there will be some line changes per Eric Stephens of the OC Register.