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Memphis Tigers vs. Houston Cougars Betting Odds, College Football Pick

Houston owns five straight wins over Memphis, and four straight covers, including victories in each of the last two seasons. In a big game in the AAC West Division, the first-place Cougars host the third-place Tigers Saturday night.

Point spread: Cougars opened as five-point favorites, according to sportsbooks monitored by Odds Shark. (Line updates and matchup report)

College football pick, via Odds Shark computer: 37.2-34.3 Cougars

Why the Memphis Tigers can cover the spread

Memphis just had a 15-game winning streak snapped by a somewhat shocking 45-20 defeat at the hands of Navy last week.