Clemson owns a four-game winning streak in the rivalry with South Carolina, outscoring the Gamecocks by an average of 41-17 and going 3-1 against the spread in the process. The Tigers shoot to make it five straight Palmetto Bowl victories Saturday night at Death Valley.
College football point spread: The Tigers opened as 26.5-point favorites, according to sportsbooks monitored by OddsShark. (Line updates and matchup report)
College football betting pick, via OddsShark computer: 52.0-18.2 Tigers (College football picks on every game)
Check out the OddsShark podcast on iTunes or Spotify or at OddsShark.