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Clemson Tigers vs. Boston College Eagles Odds, College Football Betting Pick

Clemson owns seven straight wins in the series with Boston College, but the Eagles are 4-3 against the spread over that span, keeping several games close as underdogs. Boston College is getting a bunch of points again for Saturday evening's big game with the Tigers up in Chestnut Hill.

College football point spread: The Tigers opened as 17.5-point favorites, according to sportsbooks monitored by OddsShark. (Line updates and matchup report)

College football betting pick, via OddsShark computer: 45.3-25.8 Tigers (College football picks on every game)

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