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ESPN.com · Sep 28, 2017

ACC Week 5 picks: Can Clemson win another tough ACC road game?

We have yet another major ACC showdown in Week 5, as No. 2 Clemson takes on another top-15 conference opponent on the road. Will the Tigers come out with a win the way they did in Louisville? Clemson has the nation's longest win streak against ranked opponents, with seven.

Visit our college football PickCenter page for additional information on these games and many more.

No. 14 Miami (2-0, 0-0) at Duke (4-0, 1-0), 7 p.m. Friday, ESPN

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