Former world number one Novak Djokovic fell to a surprise defeat by Slovakian qualifier Martin Klizan in the second round of the Barcelona Open.
Klizan, ranked 140th in the world, beat 12th-ranked Djokovic 6-2 1-6 6-3.
The Serb hit 19 winners but struggled with his backhand, notching 22 unforced errors and winning just eight of 13 points at the net.
Defending champion Rafael Nadal plays fellow Spaniard Roberto Carballes Baena later on Wednesday.
Djokovic, a 12-time Grand Slam champion, has failed to reach the last eight in any of his five tournament appearances since making his return from an elbow injury.