The San Francisco 49ers lost Jimmy Garoppolo to a potentially devastating knee injury in Week 3 against the Kansas City Chiefs, but that was also just one of several notable injuries on both sides of the roster. It reflects extensive in the latest snap count, which is posted below. You can also view the gamebook PDF.
The big change obviously was Garoppolo. He went down with a knee injury on what would prove to be the penultimate offensive snap of the game. C.J. Beathard came on for a snap and appeared to throw a touchdown pass to George Kittle.