Stanford became the first No. 1 seed to fail to reach the Sweet 16 since 2009, falling to No. 8 Ole Miss 54-49 on Sunday night at Maples Pavilion.
The Cardinal had not fallen in the second round since 2007; their 14 consecutive appearances in the Sweet 16 were the third-best mark of all time behind Connecticut (28) and Tennessee (27). Winners of the 2021 national title, they had been to two consecutive Final Fours.
Stanford did not lead the entire game, with Ole Miss jumping ahead by as many as 13 points midway through the third.