The Red Devils duo will be forced under the knife after picking up knocks in a Europa League win over Anderlecht, but no return dates have been set
Zlatan Ibrahimovic requires surgery after sustaining knee ligament damage, but Jose Mourinho is unwilling to give further details about the status of the striker.
Ibrahimovic suffered the injury against Anderlecht in Thursday's Europa League quarter-final at Old Trafford, with Marcos Rojo sustaining similar damage the same match.
Mourinho was reluctant to set a timescale for the pair's recovery - with Ibrahimovic's United contract set to expire at the end of the current campaign - but confirmed both players will go under the knife.