New signing Jeffrey Schlupp is set to feature for Crystal Palace after joining from Leicester for around £12m.
Wilfried Zaha and Bakary Sako are both away on international duty but James McArthur, Fraizer Campbell and Scott Dann are all fit after recent injuries.
Everton defender Leighton Baines is expected to recover from a rib injury, while goalkeeper Maarten Stekelenburg is fit to return after a month out.
Morgan Schneiderlin and Ademola Lookman could make their first starts.
MOTD COMMENTATOR'S NOTES
Jonathan Pearce: "Forget the FA Cup win over Bolton, Crystal Palace are in dire trouble.