Northwestern released its depth chart Monday for its Week 3 game at Duke, and the main changes of note are on the offensive line. Ian Park is now listed as the starting center, with Brad North backing him up. Connor Mahoney is now the starter at left guard:
Changes in bold italic
| Starter/1st String | Backup/2nd String | |
| Quarterback | Clayton Thorson | Zack Oliver OR Matt Alviti |
| Running Back | Justin Jackson | Warren Long |
| Z-Receiver | Austin Carr | Macan Wilson |
| Y-Receiver | Christian Jones | Flynn Nagel |
| X-Receiver | Miles Shuler | Mike McHugh |
| Superback | Dan Vitale | Garrett Dickerson |
| Left Tackle | Geoff Mogus | Adam DePietro |
| Left Guard | Connor Mahoney | J. |