The Bucs and Colts are both 5-5 on the season, and considering their circumstances, probably happy to be there. They're also both 5-1 against the spread over their last six games. In an interesting inter-conference matchup Tampa Bay visits Indianapolis Sunday afternoon.
Point spread: Colts opened as three-point favorites; the total was 47 early in the week, according to sportsbooks monitored by Odds Shark. (Line updates and matchup report)
NFL pick, via Odds Shark computer: 27.0-20.0 Buccaneers
Why the Buccaneers can cover the spread
The Bucs are 3-1 over their last four games, after embarrassing the Eagles in Philly last week 45-17.