Manchester City kick off their defence of the Premier League title at newly promoted Burnley, while Mauricio Pochettino will begin his reign at Chelsea against Liverpool.
Burnley, managed by City legend Vincent Kompany, is the opening game of the season on Friday, Aug. 10.
Luton Town, who are back in the English top flight for the first time since 1992, begin away at Brighton while fellow Premier League newcomers Sheffield United play Crystal Palace at Bramall Lane.
Newcastle United face a tricky start to their season, playing five of last season's top eight in their first five fixtures.