The Reds are looking for a morale-boosting three points in a bid to enhance our prospects of finishing in the top four of the Premier League this term.
Spurs have been inconsistent under Antonio Conte but have pulled off some really impressive wins against Manchester City, Leeds United and Everton recently.
The big news is that there is no Bruno Fernandes in the matchday squad but David De Gea, contrary to some earlier reports, does start in goal.
Cristiano Ronaldo returns in attack and Raphael Varane is back from his Covid-19 absence to partner captain Harry Maguire.