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Angels upended despite Upton's home run

ANAHEIM -- A Justin Upton two-run home run in the fourth inning, one of his two extra-base hits on the night, and a Luis Valbuena solo shot were not enough to compensate for JC Ramirez's erratic night on the mound Saturday night as the Angels' three-game winning streak was snapped in a 7-3 loss to the A's at Angel Stadium.

Ramirez was pulled after two turbulent innings, in which the right-hander walked five batters and gave up three earned runs.

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Ramirez, who underwent stem-cell therapy to treat a partially torn ulnar collateral ligament in his right elbow last summer, confirmed after the game that he had experienced some forearm tightness during Saturday's game -- enough for manager Mike Scioscia to pull the plug on him after just 55 pitches.