INDIANAPOLIS -- Quarterback Andrew Luck has started each of the past three seasons 0-2. He has no idea what it’s like to start a season 0-3 though.
Luck and the Indianapolis Colts will try to avoid having that happen when they take on the San Diego Chargers in a game between two teams that have dealt with their fair share of injuries.
Here are several areas to keep an eye on:
Replacing Moncrief: This is the first of as many as six games the Colts will play with receiver Donte Moncrief (shoulder).