All times CT.
| Home: 4-2 | Away: 1-4 | Neutral: 0-0Record: 5-6 (2-5) | ||
| Date | Opponent | Result/Time |
| Fri, Sep 4 | Kent State | W 52-3 |
| Sat, Sep 12 | Western Illinois | W 44-0 |
| Sat, Sep 19 | at North Carolina | L 48-14 |
| Sat, Sep 26 | Middle Tennessee | W 27-25 |
| Sat, Oct 3 | Nebraska | W 14-13 |
| Sat, Oct 10 | at Iowa | L 29-20 |
| Sat, Oct 24 | Wisconsin | L 24-13 |
| Sat, Oct 31 | at Penn State | L 39-0 |
| Sat, Nov 7 | at Purdue | W 48-14 |
| Sat, Nov 14 | Ohio State | L 28-3 |
| Sat, Nov 21 | at Minnesota | L 32-23 |
| Sat, Nov 28 | Northwestern (Soldier Field, Chicago, IL) | 2:30pm ESPNU |