Manchester United will be without defender Eric Bailly, who has injured his ankle playing for the club's under-23 side.
Manager Jose Mourinho otherwise has a full-strength squad at his disposal.
Hull defender Curtis Davies is out with a hamstring injury, but new loan signing Andrea Ranocchia is available.
Ahmed Elmohamady is still at the Africa Cup of Nations, while Alex Bruce, Markus Henriksen, Will Keane, Ryan Mason and Moses Odubajo are all out.
MOTD COMMENTATOR'S NOTES
Martin Fisher: "Having lost to Hull last week in the second leg of their EFL Cup semi-final, there's no way United will be taking this game lightly.