About midway through the first quarter on Wednesday night, the Clippers led the Warriors 10-9.
At the end of the first frame, Golden State led 37-19.
"We set the tone early, just turning the ball over," Clippers head coach Doc Rivers said. "I thought they took us out of our stuff. We stopped trusting, and I really never thought we got our spirit back after the beginning."
In the first 12 minutes, the Clippers turned the ball over nine times and the Warriors turned the giveaways into eight points.
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Blake Griffin alone coughed it up five times.