The Reds got off to a quick start in route to their third consecutive win over the St. Louis Cardinals. The Reds began the first inning with back-to-back singles by Phillips and Votto. Later on in the inning, back-to-back doubles by Bruce and Byrd gave the Reds a 2-0 lead. Eugenio Suarez hit another single in the inning to give the Reds a 3-0 lead. That would prove to be all the runs the Reds would need.
The Cardinals cut the lead to 3-2 in the third inning on a Matt Carpenter 2-run home run. That was all Reds starter Anthony DeSclafani would allow.