Slugger Domingo Santana crushed a grand slam in the fourth inning, and the Brewers put the first two men aboard in the fifth inning against Diamondbacks lefty Patrick Corbin, bringing an early end to his day as Milwaukee had a 6-1 lead in the top of the fifth.
Corbin allowed a pair of singles and a walk in the fourth, loading the bases for Santana, who drilled what appeared to be a high change-up out to right-center field. It was his first career grand slam.
Manny Pina and Jonathan Villar opened the bottom of the fifth with consecutive singles, bringing Diamondbacks manager Torey Lovullo from the dugout to make a pitching change.