Highlights from Week 4:
Click Here for Full Recaps From Each Game
Through four weeks of the 2016 season, the American Athletic Conference ranks fourth among the 10 NCAA FBS conferences in nonconference winning percentage.
| Conference | W-L | Pct. | |
| 1. | SEC | 25-7 | .781 |
| 2. | Big Ten | 32-9 | .780 |
| 3. | ACC | 31-9 | . |