Sorry, fight fans ... Floyd Mayweather's making it clear -- the Manny Pacquiao tilt is off.
"I don't give a f*** about what's going on with Pacquiao," Floyd tells TMZ Sports.
Remember ... Floyd was singing a little different tune just a few weeks ago -- when he said, "I'm coming back to fight Manny Pacquiao this year another 9 figure pay day on the way."
But, Floyd tells us that's now off, saying, "We not going to make that happen right now.