It was a season to forget in Indianapolis in 2021 as the Colts were in pole position to head into the postseason before dropping each of their final two games of the regular season including an inexcusable home loss to the Jacksonville Jaguars. As they look to top the AFC South for the first time since 2014, we examine their odds to do so over at BetMGM.
Indianapolis Colts (2021 Record: 9-8)
Biggest Addition: Matt Ryan
The Colts will start their fifth quarterback in five years on Week 1 with the addition of former Falcons signal-caller Matt Ryan.