Sometimes the most profitable overall course of action is to make a choice that will cause you to lose a hand more often. It may sound ridiculous, but it's true. Let me explain.
Let's say you could raise a turn card and win a hand 95 percent of the time. But if you don't raise you enter a really profitable river situation, where you only win the actual pot 75 percent of the time. However, when you win, you win big, and when you lose, you don't put in extra money.
Three times out of four you'll scoop a deliciously bloated pot.