The teams in the AP Top 25 will try to replicate the success No. 10 Penn State and No. 16 UCF experienced Friday during the Saturday slate of Week 4 games.
Eleven of the ranked teams in action Saturday are on the road, with most of those programs partaking in conference play.
Independent No. 8 Notre Dame, No. 13 Virginia Tech and No. 23 Boston College face nonconference foes on the road, while everyone else embarks on intraconference trips.
The SEC and Pac-12 possess the only matchups between ranked foes Saturday, and the game out west could alter the thinking of the College Football Playoff selection committee a bit.