Ole Gunnar Solskjaer has already confirmed Di’Shon Bernard, Ethan Laird and Dylan Levitt will start the Group L encounter, each making their senior bow.
If any substitutes are introduced, presuming Luke Shaw, Axel Tuanzebe and Jesse Lingard all start, with Lee Grant definitely keeping goal, then the tally of new faces will obviously increase.
By our reckoning, the most debutants fielded by the club in a single game since World War I is five. This has been happened on four occasions over the years, most recently in the Premier League opener of the 2015/16 season, against Tottenham Hotspur at Old Trafford.