8:20 p.m. ET | NBC
Matchup rating: 79.8 | Spread: KC -6.5 (56.5)
What to watch for: Who will show up for the Raiders on defense? Las Vegas had a statement game defensively in the victory at Arrowhead Stadium last month, but 10 of the 11 players on their reserve/COVID-19 list are defensive players. Defensive end Clelin Ferrell, who tested positive, is likely out, but the rest, including safety Johnathan Abram and defensive tackles Maliek Collins and Johnathan Hankins, will be eligible to play should they test negative this weekend.