Crystal Palace face a blockbuster opening six games to their Premier League season starting with a trip to Champions League holders Chelsea.
After then hosting new boys Brentford and travelling to West Ham United, the Eagles face another two of the Big Six in September when they entertain Tottenham Hotspur before visiting Liverpool - followed by a home clash against bitter rivals Brighton.
Palace end the campaign with what appears another tough test when they host Manchester United on the final day of the season.
Read the full list below:
14/08/2021 15:00 Chelsea (a)
21/08/2021 15:00 Brentford (h)
28/08/2021 15:00 West Ham United (a)
11/09/2021 15:00 Tottenham Hotspur (h)
18/09/2021 15:00 Liverpool (a)
25/09/2021 15:00 Brighton (h)
02/10/2021 15:00 Leicester City (h)
16/10/2021 15:00 Arsenal (a)
23/10/2021 15:00 Newcastle United (h)
30/10/2021 15:00 Manchester City (a)
06/11/2021 15:00 Wolves (h)
20/11/2021 15:00 Burnley (a)
27/11/2021 15:00 Aston Villa (h)
30/11/2021 19:45 Leeds United (a)
04/12/2021 15:00 Manchester United (a)
11/12/2021 15:00 Everton (h)
14/12/2021 20:00 Southampton (h)
18/12/2021 15:00 Watford (a)
26/12/2021 15:00 Tottenham Hotspur (a)
28/12/2021 15:00 Norwich City (h)
01/01/2022 15:00 West Ham United (h)
15/01/2022 15:00 Brighton (a)
22/01/2022 15:00 Liverpool (h)
08/02/2022 19:45 Norwich City (a)
12/02/2022 15:00 Brentford (a)
19/02/2022 15:00 Chelsea (h)
26/02/2022 15:00 Burnley (h)
05/03/2022 15:00 Wolves (a)
12/03/2022 15:00 Manchester City (h)
19/03/2022 15:00 Newcastle United (a)
02/04/2022 15:00 Arsenal (h)
09/04/2022 15:00 Leicester City (a)
16/04/2022 15:00 Everton (a)
23/04/2022 15:00 Leeds United (h)
30/04/2022 15:00 Southampton (a)
07/05/2022 15:00 Watford (h)
15/05/2022 15:00 Aston Villa (a)
22/05/2022 16:00 Manchester United (h)
All fixtures are subject to change once live TV schedule has been finalised.