Week 12 gives us our first 16-game slate since Week 3, but also comes with three Thursday games due to the Thanksgiving holiday, so lineup decisions become a little tougher, especially if you’re dealing with injuries for players with weekend games.
When composing my rankings, the biggest thing that jumped out to me was the matchups at the quarterback position. Other than Arizona Cardinals quarterback Carson Palmer and New York Giants quarterback Eli Manning, the top-scoring fantasy quarterbacks or those in that conversation are dealing with some tough matchups.
At the top of the heap is Tom Brady taking on the Denver Broncos, which is difficult enough at full strength, but the injury bug has hit the New England Patriots hard in recent weeks.