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Cardinals WR John Brown suffering leg pains stemming from sickle-cell trait

John Brown missed his third straight practice Friday, and afterwards, Cardinals coach Bruce Arians shed some light on the receiver's injury.

We knew Brown had a hamstring issue, which is something that plagued his 2015 season, but now we know the root cause.

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A blood test performed on the wideout concluded that Brown has sickle-cell trait, which the team believes has caused some of his injury problems.

Some people with SCT [sickle-cell trait] have been shown to be more likely than those without SCT to experience heat stroke and muscle breakdown when doing intense exercise, such as competitive sports or military training under unfavorable temperatures( very high or low) or conditions.